Schematic illustration of in vivo fluorescence sensing using a microneedle (IMAGE)

Innovation Center of NanoMedicine

Schematic illustration of in vivo fluorescence sensing using a microneedle

Caption

(a) PLLA microneedle with high-aspect ratio (500 µm in base diameter, 200 µm in top diameter, and 2000 µm in length) with a hydrogel block (100 µm in diameter and 100 µm in length, total volume: 0.79 nL) at the needle tip. (b) Schematic illustration of functionalized microneedle tip. The hydrogel block enables the extraction of biological molecules by diffusion and serves as a reaction space for in situ molecular sensing.

Credit

Takehara's Lab in University of Tokyo

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