Structurally distinct neurokinin-1 receptor antagonists show antidepressant-like effects in preclinical models (IMAGE)

Korea University College of Medicine

Structurally distinct neurokinin-1 receptor antagonists show antidepressant-like effects in preclinical models

Caption

Machine-learning–guided screening identified a structurally novel NK1 receptor antagonist that reduced depressive-like behavior and neuroinflammation in mouse models.

Credit

Kim Hong-Rae from Korea University

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