Macrophages in lung tissue (IMAGE)

Texas Biomedical Research Institute

Macrophages in lung tissue

Caption

Macrophages (red), including proliferating macrophages (green), in lung tissue. Macrophage turnover is significantly reduced in the lungs of cART+3HP-treated macaques (right) compared to animals treated with cART alone (middle) or untreated controls (left). While reduced turnover indicates decreased cellular replacement, additional functional changes observed in these macrophages suggest that the population remains dysregulated and retains inflammatory characteristics during chronic infection, despite treatment.

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Texas Biomed

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