How O-mannose glycan branching enables complex sugar formation in the brain (IMAGE)

Institute for Glyco-core Research (iGCORE), Tokai National Higher Education and Research System

How O-mannose glycan branching enables complex sugar formation in the brain

Caption

The brain-specific enzyme GnT-IX adds a side branch to O-mannose glycans on proteins, creating a scaffold that allows other enzymes to efficiently build keratan sulfate and other complex sugar structures.

Credit

Yasuhiko Kizuka, Institute for Glyco-core Research (iGCORE), Gifu University

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