Electron microscopy images of synapse treated with or without tau oligomers (IMAGE)

Buck Institute for Research on Aging

Electron microscopy images of synapse treated with or without tau oligomers

Caption

Electron microscopy images of human neuron synapses 7 or 14 days after a 30-minute exposure to tau oligomers or vehicle control. In vehicle-treated neurons synaptic vesicles (red circles) are clustered near the active zone (red arrows), whereas tau oligomer-treated neurons show increased vesicle number with reduced clustering and a more dispersed vesicle distribution. Scale bar: 200 nm. Magnification: 50,000x

Credit

Kristeen Pareja-Navarro. PhD, Buck Institute for Research on Aging

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