LimbLab: a tool to visualise development in 3D (IMAGE)

European Molecular Biology Laboratory

LimbLab: a tool to visualise development in 3D

Caption

Three-dimensional image of a developing limb bud generated using LimbLab. It shows where key genes are active during early limb formation. Sox9 (magenta) marks the cells that will become cartilage and already outlines the basic structure of the future limb skeleton. BMP (cyan) appears in surrounding and complementary regions, where it plays an important role in coordinating growth and signalling between tissues.

Credit

Laura Aviñó-Esteban/EMBL

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License

CC BY-NC-SA

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