Influence of Endoplasmic Reticulum Stress on Fatty Liver and Liver Cancer (IMAGE)

Industrial Cooperation & research Planning team, Hanyang University ERICA

Influence of Endoplasmic Reticulum Stress on Fatty Liver and Liver Cancer

Caption

Endoplasmic reticulum stress and unfolded protein response dysregulation propel lifestyle-associated fatty liver disease (metabolic dysfunction-associated steatotic liver disease, affecting 30% globally) from simple steatosis to metabolic dysfunction-associated steatohepatitis, cirrhosis, and hepatocellular carcinoma, via mechanisms like IRE1-driven lipotoxicity, cell death, and inflammation.

Credit

Ju Youn Kim from Hanyang University ERICA

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