TRPV4 Ion Channel Connection to Itch Behavior (IMAGE)
Caption
TRPV4, an ion channel, is found in neurons classically associated with touch, called Aβ low-threshold mechanoreceptors. New research indicates that TRPV4 can generate itch, but it also helps trigger a negative feedback signal, a neural message that tells the spinal cord and brain that scratching has been sufficient.
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Image Courtesy of Roberta Gualdani
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