A dual-compound strategy rewires the injured spinal cord. (IMAGE)
Caption
A dual-compound strategy rewires the injured spinal cord. This graphic shows how a paired therapy combining luteolin (Lut) and astragaloside IV (AST)—two bioactive compounds derived from the traditional herb pair Huangqi and Dangshen—helps the injured spinal cord recover. After spinal cord injury, excessive reactive oxygen species (ROS) and neuroinflammation drive widespread neural damage. In contrast to untreated injury, the Lut–AST combination dampens oxidative stress, limits inflammation, preserves neural structure, and promotes reconnection of damaged nerve fibers, ultimately leading to improved functional recovery.
Credit
Precision Clinical Medicine
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CC BY