A complication of immune checkpoint inhibitors (IMAGE)

Cincinnati Children's Hospital Medical Center

A complication of immune checkpoint inhibitors

Caption

When immune checkpoint inhibitors are used in cancer treatment, in some cases it can lead to severe inflammation and damage to heart tissue. Histology images of mouse heart tissue illustrate the differences between unaffected control tissue (top) and inflamed tissue (bottom) following checkpoint inhibitor administration. The inflamed tissue contains many more active immune cells including myeloid cells (white). Researchers at Cincinnati Children’s report discovering a method that may prevent this type of inflammation.

 

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Cincinnati Children's

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