Surprising culprit leads to chronic rejection of transplanted lungs, hearts (IMAGE)
Caption
A new study from researchers at WashU Medicine has identified lymphatic vessels and their cargo — a sugar molecule called hyaluronan (shown in pink) — as critical drivers of chronic rejection in transplanted lungs and hearts. A lung transplanted between genetically identical mice is laden with scar tissue full of hyaluronan (top half of image). Following a treatment to promote growth of lymphatic vessels, hyaluronan accumulation is markedly reduced (bottom).
Credit
Hailey Shepherd
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Credit Hailey Shepherd
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