Imaging of individuals suspected of having Alzheimer.'s disease (AD), LATE, and mixed LATE and AD co-pathology (IMAGE)

Society of Nuclear Medicine and Molecular Imaging

Imaging of individuals suspected of having Alzheimer.'s disease (AD), LATE, and mixed LATE and AD co-pathology

Caption

 Visual Abstract. Comparison of FDG PET 3D-SSP z score maps and transaxial slices of the temporal lobe, along with corresponding MRI images, among individuals suspected of having Alzheimer's disease (AD), LATE, and mixed LATE and AD co-pathology. Color-coded areas on the 3D-SSP maps represent more severe metabolic reductions. Patients with LATE and LATE+AD show a distinct pattern of decreased FDG uptake in the medial temporal lobe, whereas AD and LATE+AD show the well-known pattern of decreased FDG uptake in the posterior cingulate cortex, precuneus, and parieto-temporal association cortices.

Credit

Image created by Pei Ing Ngam, Department of Diagnostic Imaging, National University Hospital Singapore, Singapore, and Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, Utah.

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