Mannose metabolic pathway senses glucose supply and regulates cell fate (IMAGE)

Institute for Glyco-core Research (iGCORE), Tokai National Higher Education and Research System

Mannose metabolic pathway senses glucose supply and regulates cell fate

Caption

Low metabolic flux of glucose into mannose pathway initiates alterations in cancer cells, at least in part through N-glycosylation defects, leading to cell fate decisions.

Credit

Yoichiro Harada, Institute for Glyco-core Research (iGCORE), Nagoya University

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