Molecular target drives immunogenicity in cancer immunotherapy (IMAGE)
Caption
Figure (A) Mechanistic view of PlatinER induced ICD through PTP1B targeting. (B) Data illustrating ability of PlatinER and Pt-NHC to establish immunity against colorectal cancer in research models. (C) Schematic diagram illustrating target profiling processes, including photoaffinity labeling, click reaction, enrichment, tandem mass tags (TMT) quantitative proteomic analysis and target prioritisation.
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National University of Singapore
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