Single-cell atlas reveals fibrotic drivers of rotator cuff scar formation (IMAGE)

Editorial Office of West China School of Stomatology, Sichuan University

Single-cell atlas reveals fibrotic drivers of rotator cuff scar formation

Caption

Single-cell RNA sequencing of human rotator cuff tendon samples identifies pro-fibrotic stem cells, senescent tenocytes, scar-associated macrophages, and transitioning endothelial cells that collectively drive persistent extracellular matrix deposition and scar formation.

Credit

Prof. Jianzhong Hu and Prof. Hongbin Lu from Central South University, China Image Source Link: https://doi.org/10.1038/s41413-025-00501-5

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