Broad and potent immune activation with DoriVac vaccines (IMAGE)

Wyss Institute for Biologically Inspired Engineering at Harvard

Broad and potent immune activation with DoriVac vaccines

Caption

DoriVac DNA origami vaccines consist of tiny self-folding and assembling square block-shaped nanostructures that on one face present adjuvant molecules (green) and on the other pathogen-derived antigens (magenta). The nanostructured vaccines produced a potent activation of dendritic cells and, in turn, significantly greater and broader activation of humoral antibody producing and cellular CD4+ and CD8+ T cell responses in experimental models.

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Wyss Institute at Harvard University

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