Dual-mode TRPV3 activation for systemic antibody response mediated by FPP and Carvacrol (IMAGE)
Caption
This hand-painted oil artwork portrays the epidermal microenvironment as a layered barrier landscape. The lower crimson band represents the epidermis, where keratinocyte-intrinsic FPP accumulation activates TRPV3 and ignites Ca²⁺-dependent mediator release, rendered as rising luminous streams. Above, immune cell–like orbs suggest dendritic-cell recruitment and lymphocyte convergence into germinal centers, amplifying systemic IgG—an axis linked to lupus when dysregulated and inspiring vaccine adjuvant design.
Credit
Prof. Haijing Wu from Central South University, Hunan, China Image source link: https://link.springer.com/journal/44466/updates/27784804
Usage Restrictions
Credit must be given to the creator. Only noncommercial uses of the work are permitted. No derivatives or adaptations of the work are permitted.
License
CC BY-NC-ND