Schematic depiction of the preparation of FeOOH NRs for STT-based tumor treatment. (IMAGE)

Science China Press

Schematic depiction of the preparation of FeOOH NRs for STT-based tumor treatment.

Caption

Schematic illustration of the tribocatalysis mechanism based on FeOOH nanocatalysts for tumor therapy and FeOOH NRs-mediated STT for generating abundant ROS to induce the mitochondrial and DNA damage, promoting PANoptosome assembly and ultimately triggering PANoptosis (pyroptosis, apoptosis and necroptosis).

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© 2026 Xinran Song et al.

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