Elucidating the Functional Dynamics of DNASE1L2 Intron Retention in Tuberculosis Progression. (IMAGE)
Caption
Based on public datasets, this work depicted the dynamic alterations of intron retention (IR) events and their correlation with tuberculosis (TB) progression innovatively. The splicing dynamics of DNASE1L2-IR are a promising marker for monitoring TB progression. Host cells can regulate M. tuberculosis DNA degradation and inflammation levels via DNASE1L2-IR to control TB progression. Created with biorender.com
Credit
Bingwu Ying, West China Hospital of Sichuan University, China
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