CFHR1 is involved in IgA immune complex formation (IMAGE)

Fujita Health University

CFHR1 is involved in IgA immune complex formation

Caption

Complement pathway proteins are involved in immunoglobulin A-containing immune complex (IgA-IC) formation and deposition in the kidneys. Elevated complement factor H-related protein 1 (CFHR1) may be a biomarker for susceptibility to IgA nephropathy. Immunosuppressive treatment reduces IgA-IC formation and increases CFHR3 in kidney tissue.

Credit

Professor Kazuo Takahashi from Fujita Health University School of Medicine, Japan

Usage Restrictions

Cannot be reused without permission.

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.