Acoustic rising bubbles generate strong shear flows and enable rapid mixing and cell manipulation. (IMAGE)
Caption
(A) Setup comprising a robotic arm, a glass capillary, a syringe pump, and an acoustofluidic device with integrated imaging. (B) Large-scale shear flow produced by rising bubbles. (C) Schematics of different flow modes: single oscillation, buoyancy-driven rise, acoustic rising, and bubble array mixing. (D) Enhanced mass transfer through disrupted laminar flow. (E) Accelerated chemical reactions by bubble microstreaming. (F) Shear-induced cell membrane permeabilization and lysis. DoF, degree of freedom.
Credit
Chenhao Bai, Beijing Institute of Technology.
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