Breast Cancer Cells (IMAGE)
Caption
In healthy tissues, seen in the top two panels here, TYK2 (green) is found on the cell membrane and colocalizes with E-cadherin (red), a protein helps that maintain cellular adhesion and tissue integrity. In tumors, shown in the bottom two panels, TYK2 is spread throughout the cell and no longer colocalizes with E-cadherin. This phenomenon allows cancer cells to more easily spread.
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UC San Diego Health Sciences
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