Fcγ Receptor Binding is Linked to Antibody Anaphylaxis (IMAGE)
Caption
In tumor-bearing mouse models, anti-programmed death-ligand 1 antibodies with stronger Fcγ receptor binding were associated with higher antidrug antibody levels and anaphylaxis, with tumor-associated myeloid cells implicated in the capture of these antibodies.
Credit
Professor Hiroto Hatakeyama from Chiba University, Japan
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Original content