Ellen M. Lavoie Smith, PhD, MSN, Interim Associate Dean of Research and Scholarship at the University of Alabama at Birmingham School of Nursing (IMAGE)
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“Since we know duloxetine is effective at treating painful neuropathy caused by neurotoxic chemotherapy drugs, we wanted to see if the medication could also prevent the side effect from developing in the first place,” said Ellen M. Lavoie Smith, PhD, MSN, Interim Associate Dean of Research and Scholarship at the University of Alabama at Birmingham School of Nursing and study chair for Alliance A221805. “The results show that duloxetine is not more effective than a placebo at preventing neuropathy caused by chemotherapy in patients with colorectal cancer.”
Led by Dr. Smith, this is the largest randomized trial to date specifically designed to evaluate whether duloxetine can prevent oxaliplatin‑induced peripheral neuropathy.
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University of Alabama at Birmingham School of Nursing
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