DSBs and DSB repair mechanisms using common genome editing platforms (ZFN, TALEN, and CRISPR/Cas9). (IMAGE)
Caption
DSB, DNA double-strand break; TALEN, transcription activator-like effector nuclease; ZFN, zinc finger nuclease; CRISPR, clustered regularly interspaced short palindromic repeats; Cas, CRISPR-associated protein.
Credit
Parto Toofan, Mark Singh, Andrew Brooks, Keith McLuckie
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CC BY-NC-ND