Histamine-related gene expression in the human brain. (IMAGE)

King's College London

Histamine-related gene expression in the human brain.

Caption

Red indicates parts of the brain with more histamine-related gene expression, blue regions have comparatively less. The genes (HDC, HNMT, ALDH7A1, MAOB, HRH1, HRH2, HRH3, HRH4) play many different roles in histamine signalling, including histamine production (HDC), histamine breakdown (HNMT) or encoding histamine receptors (HRH1, HRH2, HRH3, HRH4). Figure adapted from Martins et al. 2026, Nature Mental Health DOI 10.1038/s44220-026-00637-1. 

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Dr Daniel Martins in Nature Mental Health

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