Figure 1 (IMAGE)

Tohoku University

Figure 1

Caption

An overview of the study. Left: Dopamine neurons (purple) project from the brainstem to the striatum to regulate motor function, while a distinct population (red), identified in 2021, projects to the entorhinal cortex and supports memory formation. Middle: In an Alzheimer's disease mouse model, dopamine levels (yellow circles) in the entorhinal cortex are markedly reduced, leading to disrupted neural activity and impaired memory. Right: Treatment with Levodopa restores dopamine levels, normalizes neural activity, and improves memory.

Credit

Tatsuki Nakagawa et al.

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