Representative SV2A PET images comparing synaptic density in healthy and disease states. (IMAGE)
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Figure 1. Representative SV2A PET images comparing synaptic density in healthy and disease states. The left panel shows [18F]SynVesT-1 PET distribution volume (VT) maps of the brain and spinal cord in a naïve control mouse and a mouse with experimental autoimmune encephalomyelitis (EAE), a model of multiple sclerosis. The right panel shows [11C]UCB-J PET images of the brain of a 46-year-old male health control (left) 43-year-old female MS patient (right).
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Courtesy of SNMMI.
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