Key Interactions and Substitution Site (Red Circle) Between Existing Inhibitor 15b and CYP Residues (IMAGE)

Toyohashi University of Technology (TUT)

Key Interactions and Substitution Site (Red Circle) Between Existing Inhibitor 15b and CYP Residues

Caption

 Red, blue, and yellow lines represent sites for coordination bonds with heme iron, hydrogen bonds with residues, and CH-π bonds, respectively. The red circle marks the site for introducing substituents when searching for novel compounds based on inhibitor 15b.

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COPYRIGHT(C)TOYOHASHI UNIVERSITY OF TECHNOLOGY. ALL RIGHTS RESERVED.

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