Rat Kidneys Grown in Mice Offer New Insights into Addressing Organ Donor Shortages (IMAGE)
Caption
Rat embryonic stem cells (red) generate kidney tissue in Osr1-deficient mouse embryos via interspecies blastocyst complementation. The nephron structure and collecting duct (E-cadherin, green) are predominantly derived from the rat donor cells. The DNA (blue) was used for counterstaining.
Credit
Shunsuke Yuri and Ayako Isotani, Nara Institute of Science and Technology
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License
CC BY-SA