Genetics likely made some people extra susceptible to obesity as society changed (IMAGE)
Caption
Association (+ 95% CIs) between PGI and BMI (kg/m2) by cohort, age, and PGI (adulthood or childhood). Derived from separate linear mixed effects models with the association between PGI and BMI allowed to vary by age (two natural splines). Adjustment was made for age (two natural splines), sex, first 10 genetic principal components, and a person-specific random intercept. Estimates were weighted using recruitment weights.
Credit
Wright et al., 2026, PLOS Genetics, CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0/)
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Credit must be given to the creator.
License
CC BY