Semiconductor SERS Strategies Enable Precise Detection. (IMAGE)
Caption
This schematic illustrates the four core enhancement strategies—energy level customization, amorphization, quasi-metallization, and morphology control—that underpin the recent leap in semiconductor-based surface-enhanced Raman scattering (SERS). These rationally designed material approaches modulate electronic band structures and charge transfer processes, achieving high sensitivity, selectivity, and stability. The resulting substrates are being applied in transformative fields such as virus detection (e.g., SARS-CoV-2 identification), food safety monitoring (e.g., trace bisphenol A), cancer diagnosis (e.g., early lung cancer biomarker detection), and volatile organic compound sensing, paving the way for next-generation analytical platforms in healthcare, environment, and security.
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Nano Research, Tsinghua University Press
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