In vivo Electroporation: From Electrical Stimulation to Precision Delivery—An Integrated Overview (IMAGE)
Caption
“From ‘Applying Current’ to Precise Delivery: A Holistic View”This illustration provides a comprehensive overview of in vivo electroporation (IVE), highlighting its core structures and diverse applications. By applying brief electric pulses, cell membranes are momentarily “opened,” allowing biomolecules such as DNA, mRNA, proteins, and gene-editing tools to efficiently enter target cells. Coupled with various electrode designs, IVE has been widely adopted in areas including cancer therapy, vaccination, gene therapy, and tissue regeneration, offering a delivery platform that is non-viral, safe, and spatially controllable.
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Nano research, Tsinghua University Press
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