IL-22 Promotes Epithelial Repair Through Paneth Cell Metaplasia in Ulcerative Colitis (IMAGE)

Institute of Science Tokyo

IL-22 Promotes Epithelial Repair Through Paneth Cell Metaplasia in Ulcerative Colitis

Caption

During chronic inflammation, IL-22 signaling triggers Paneth cell metaplasia in the colon. These metaplastic cells produce REG3A, an antimicrobial protein that promotes repair of the intestinal lining.

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Institute of Science Tokyo

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