Schematic illustration of the composition and structural engineering of metal-based nanomaterials as LDI-MS matrices for detecting small-molecule biomarker in CAD and HF. (IMAGE)
Caption
ig. 1 Schematic illustration of the composition and structural engineering of metal-based nanomaterials as LDI-MS matrices for detecting small-molecule biomarkers in coronary artery disease (CAD) and heart failure (HF). The design strategies encompass compositional tuning (single- and multi-component systems) and structural control (porous, core-shell, and array architectures), which together enable metabolic fingerprinting for diagnosis and subtyping of CAD and HF.
Ag: silver; Au: gold; Pd: palladium; Pt: platinum; Fe3O4: magnetite (iron oxide); Cu2O: cuprous oxide; ZnO: zinc oxide; TiO2: titanium dioxide; MOF: metal-organic framework; CAD: coronary artery disease; HF: heart failure
Credit
Li Ma, Jiao Wu, Jun Pu, Yida Huang, Kun Qian.
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CC BY-NC-ND