Pi Stacking by TRIP (IMAGE)
Caption
To directly measure pi-pi stacking, the team invented TRIP, a technique that fires a laser onto a sample and records the unique vibrational signals that return. Their test came in the form of a familiar target: the SARS-CoV-2, the virus responsible for the COVID-19 pandemic. Specifically, the researchers focused on its main protease, Mpro, a protein that holds the pathogen’s structure and helps it reproduce.
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Texas A&M University/Dr. Narangerel Altangerel
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