Schematic illustration of frequency-specific tPBM glial mechanisms in AD mice. (IMAGE)

Beijing Institute of Technology Press Co., Ltd

Schematic illustration of frequency-specific tPBM glial mechanisms in AD mice.

Caption

CW light preferentially enhances astrocyte–vascular coupling to restore vascular and protect synapses, whereas 40-Hz pulsed light promotes microglial redistribution around Aβ plaques to facilitate amyloid clearance and alleviate neurodegenerative pathology.

Credit

Ting Li, Biomedical Engineering Institute, Chinese Academy of Medical Sciences and Peking Union Medical College.

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