Dr. Andrew A. Pieper (IMAGE)

University Hospitals Cleveland Medical Center

Dr. Andrew A. Pieper

Caption

“We were encouraged to see that both human Parkinson's disease brain tissue and the brains of our three mouse models showed abnormally elevated levels of 15-PGDH,” explained Dr. Pieper. “Both genetic and pharmacologic inhibition restored redox homeostasis, which protected mice from the neuroinflammation, neuronal cell death, and motor impairment normally seen in these models of PD.”

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University Hospitals / CWRU

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