The expression of Hes6 is frequently up-regulated in tumor tissues of human gastric cancer (GC), and is associated with prognosis (IMAGE)

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The expression of Hes6 is frequently up-regulated in tumor tissues of human gastric cancer (GC), and is associated with prognosis

Caption

(A) The pan-cancer expression profile of Hes6 in the TCGA data from the GSCA database showed that Hes6 was up-regulated in GC. (B) Hes6 expression was up-regulated in paired GC data from TCGA. (C) The paired data expression map of the TNMplot database also confirmed the high expression of Hes6 in GC. (D) Gene set enrichment analysis (GSEA) of GC-related marker genes based on HES6 expression in GC data from the TCGA database. (E) Difference of HES6 expression in GC of different age groups based on the TCGA database. (F) Hes6-related overall survival curve of the GSE51105 dataset. (G) Real-time quantitative PCR (RT-qPCR) results of clinical tissue samples from 10 GC patients. (H) Western blotting results of clinical tissue samples from 5 GC patients. (I) Paired comparison statistics of Western blotting results of clinical tissue samples. ns, not significant; ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001.

Credit

Can Fang, Zhiwei Peng, Yaru Sang, Zihao Ren, Kang Wang, Nuo Xu, Ying Li, Tingting Guo, Yinan Zhu, Shangxue Yan, Kongwang Hu

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