Chac2-driven glutathione metabolism links gum disease to systemic inflammation (IMAGE)

Editorial Office of West China School of Stomatology, Sichuan University

Chac2-driven glutathione metabolism links gum disease to systemic inflammation

Caption

Schematic showing how periodontitis induces Chac2-mediated glutathione metabolic reprogramming in bone marrow neutrophils, driving their inflammatory N1 polarization and promoting systemic inflammation associated with diabetes and other comorbidities.

Credit

Professor Xuliang Deng from Peking University School and Hospital of Stomatology Image source link: https://www.nature.com/articles/s41368-026-00451-6

Usage Restrictions

Credit must be given to the creator.

License

CC BY

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.