Adhere to a biological perspective: scientists propose a framework to highlight the importance of internal constraints on prokaryotic genome evolution (IMAGE)

Institute of Botany, Chinese Academy of Sciences

Adhere to a biological perspective: scientists propose a framework to highlight the importance of internal constraints on prokaryotic genome evolution

Caption

An evolutionary framework illustrating how GC-content influences GC-skew, AT-skew, and GS-bias, thereby driving a shift between "typical" (GC-skew > 0, AT-skew < 0, and GS-bias > 0 in the leading strand) and "atypical" (GC-skew > 0, AT-skew > 0, and GS-bias > 0) modes of organization.

Credit

Wenkai Teng, Xiaofeng Zhou, Lianghu Qu, Xiao Feng, and Lingling Zheng

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