Diagram (IMAGE)

The University of Hong Kong

Diagram

Caption

Top left: Structure of the super-inert near-infrared fluorescent rotaxane dye SID-788. Top middle: SID-788 is safe for overdosage injection (500-fold of imaging dose) and exhibits efficient and ~100% renal excretion. Top right: NIR-II imaging in murine model. Principal component analysis (PCA) of NIR-II video (5–40 s post-injection) reveal reveals haemodynamics in various vessels and organs. BottumBottom: Schematic diagram of surgical imaging workflow in porcine model. Image modified from Lu et al., Nat. Photon. (2026).

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The University of Hong Kong

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