D-serine disrupts tumor immunity (IMAGE)

Keio University Global Research Institute

D-serine disrupts tumor immunity

Caption

D-serine is a metabolic byproduct that aids immune evasion by gastric cancer tumors. It increases immunosuppressive macrophage activity and reduces the numbers and function of cytotoxic T cells. This aids tumor growth and provides resistance against immune checkpoint inhibitor therapy

Credit

Shohei Suzuki and Tomohisa Sujino from Keio University, Japan

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