Diagnostic efficacy evaluation of plasma Aβ seeding activity (IMAGE)

Chinese Medical Journals Publishing House Co., Ltd.

Diagnostic efficacy evaluation of plasma Aβ seeding activity

Caption

Receiver operating characteristic (ROC) curve analysis shows that plasma β-amyloid (Aβ) seeding activity has excellent diagnostic performance in the validation cohort: (A) Distinguishing Alzheimer’s disease (AD) from cognitively normal individuals, area under the ROC curve (AUC) = 0.93 (95% CI: 0.91–0.96); (B) Distinguishing AD from non-AD dementia, AUC = 0.91 (95% CI: 0.88–0.94); (C) Distinguishing mild cognitive impairment (MCI) due to AD from cognitively normal individuals, AUC = 0.92 (95% CI: 0.87–0.96); (D) Distinguishing MCI due to AD from non-AD dementia, AUC = 0.90 (95% CI: 0.85–0.94).

Credit

Professor Jianping Jia from Capital Medical University, China

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