[18F]FDG PET/MRI in Pediatric Focal Epilepsies (IMAGE)
Caption
Figure 2: (A) Negative case (PET-negative/MRI-negative). (B) Right frontal hypermetabolic area (white arrow) in PET-positive/MRI-positive patient. On MRI, slight cortical–subcortical blurring was observed. Patient (male, 1.5-years old) underwent right frontal disconnection, and focal cortical dysplasia (FCD) IIa was diagnosed. (C) Large left parietotemporooccipital hypometabolism (white arrows) associated with cerebellar diaschisis (white asterisk) in PET-positive/MRI-positive case. Hypometabolism was more extensive than mild blurring identified by MRI in temporal lobe and was useful to guide surgical decision. Patient (male, 12-years-old) underwent left temporooccipital disconnection, and FCD IIa was diagnosed. (D) Temporal hypometabolism (white arrow) corresponding to MRI alterations (PET-positive/MRI-positive) as T2 fluid-attenuated inversion recovery hyperintensity, suggesting hippocampal sclerosis. Patient (female, 5 years-old) was drug-resistant at first evaluation but subsequently stopped having epileptic seizures, and her family decided not to proceed with surgery. (E) Right frontal PET hypometabolism (white arrow) with no MRI alterations (PET-positive/MRI-negative), possibly suggesting FCD. PET data were useful to guide SEEG implantation. Patient (female, 5-years-old) underwent right frontal disconnection, and FCD I was diagnosed.
Credit
Image created by Diego Cecchin, MD, Unit of Nuclear Medicine, Department of Medicine, University-Hospital of Padova, Italy.
Usage Restrictions
Please give appropriate credit.
License
Original content