Mechanism by which IFITM1 enhances the anti-tumor activity of DNT (IMAGE)

Science China Press

Mechanism by which IFITM1 enhances the anti-tumor activity of DNT

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IFITM1 recruits p62/SQSTM1 to mitochondria in DNT, promoting mitophagy and maintaining mitochondrial homeostasis to support cell survival and anti-tumor cytotoxicity.

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