When inherited lupus appears quieter, organ damage may still progress (IMAGE)

Sultan Qaboos University

When inherited lupus appears quieter, organ damage may still progress

Caption

This infographic explains how inherited DNASE1L3 deficiency develops and summarizes findings from 57 genetically confirmed patients in Oman and the United Arab Emirates. Although disease activity scores improved over time, kidney, lung, bone and other long-term complications became more common, highlighting the need for continued organ monitoring into adulthood.

Credit

Reem Abdwani et al., BMJ (2026)

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