super-resolution imaging comparing conventional blinking dye with self-blinking dye (IMAGE)

University of Göttingen

super-resolution imaging comparing conventional blinking dye with self-blinking dye

Caption

The image on the left shows super-resolution imaging using nanobodies with conventional blinking dye (where the blinking is poor), the image on the right shows self-blinking dye resulting in en-hanced image quality. Both images show microtubules, part of the internal structural network that helps cells maintain their shape and organize transport, in human U2OS cells, a widely used laboratory cell line.

Credit

Roman Tsukanov and the original publication in Nano Letters (2026) DOI: 10.1021/acs.nanolett.6c02799

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