scMetaTraj maps metabolism-centered trajectories (IMAGE)

International Society for Health Data Science

scMetaTraj maps metabolism-centered trajectories

Caption

scMetaTraj converts log-normalized single-cell expression into curated metabolic module scores, constructs a weighted k-nearest-neighbor graph in PCA space, and orders cells by scaled shortest-path distance from a selected root to visualize transcript-supported metabolic state variation and candidate transition regions.

Credit

Jinwei Dai et al., Med Research (2026), DOI: 10.1002/mdr2.70067.

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