Microbial and metabolite regulation of tumor immunity in HCC. (IMAGE)
Caption
The gut microbiota and their derived metabolites modulate distinct immune cell populations within the hepatic microenvironment, including macrophages, NKT cells, HSCs, and CD8⁺ and CD4⁺ T lymphocytes via key signaling molecules and pathways. These pathways can potentially promote immunosuppression and ICI resistance or enhance antitumor immunity and ICI sensitivity. Created in BioRender. https://BioRender.com/s1x1bq5
Credit
Professor Jun Yu from Chinese University of Hong Kong, China | https://link.springer.com/article/10.1007/s44466-026-00056-y
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Credit must be given to the creator. Only noncommercial uses of the work are permitted.
License
CC BY-NC